Fig. 1

PTENP1 and PTEN are concomitantly downregulated in BC tissues and cell lines. a Higher PTENP1 was observed in the nontumor tissues than BC tissues. PTEN was downregulated in BC tissues. b The levels of PTENP1 and PTEN were identified in MCF-10A and BC cell lines. c Relative PTENP1 and PTEN levels showed lower tendency in advanced stages. d The overall survival curves (OS) of PTENP1 and PTEN were presented. e PTENP1 expression was extremely higher with transfection of PTENP1 compared to the control groups. f Decreased PTENP1 level was detected in the transfected MCF-7 and T47D cells. Data are the means ± SD of triplicate determinants (*P < 0.05)