Fig. 1
From: Rewiring E2F1 with classical NHEJ via APLF suppression promotes bladder cancer invasiveness
Levels of c-NHEJ factors are deregulated in high E2F1-expressing invasive BC cells. a Cell migration (left) and invasion assays (right) in high E2F1-expressing T24 and UMUC-3 cells versus the low E2F1-expressing RT-4 cells. RT-4 values are set as 1. b Semi-quantitative PCR of c-NHEJ factors in RT-4, T24 and UMUC-3 cells. c Immunoblot depicting endogenous levels of c-NHEJ factors in RT-4, T24, and UMUC-3 cells. d Matrigel assays in E2F1-depleted T24 cells compared to the control. e Western blot analyses of c-NHEJ factors in T24 and RT-4 cells after knockdown or overexpression of E2F1, respectively, versus their corresponding controls. Asterisks denote statistically significant (** p < 0.01) changes