CDK5-mediated phosphorylation and stabilization of TPX2 promotes hepatocellular tumorigenesis

Table 1 Correlations between CDK5 expression and clinical characteristics in HCC patients

	CDK5(T-N)		Total	P
	T≦N	T > N	Total	P
Age				0.436
< 50	8	28	36
≥ 50	16	38	54
Gender				0.511
Male	19	57	76
Female	5	9	14
HBV				1.000
Positive	21	56	77
Negative	3	10	13
Liver cirrhosis				0.972
Yes	17	47	64
No	7	19	26
Tumor size(cm)				0.921
< 5	9	24	33
≥ 5	15	42	57
Histilogical differentiation				0.080
Well	4	4	8
Moderate	16	53	69
Poor	4	9	13
Serum AFP				0.873
< 25 μg/l	11	29	40
≥ 25 μg/l	13	37	50
Vessel Invasion				0.004^*
Yes	10	49	59
No	14	17	31
Recurrence				0.033^*
No	17	30	47
Yes	7	36	43
Distant Metastasis				0.941
No	18	50	68
Yes	6	16	22

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