Fig. 1

ADAR1 expression in OSCC and its clinical significance. a Differences in the expression of ADAR1 between OSCC tissue and matched non-tumor oral mucosa. The expression of ADAR1 was normalized to that of GAPDH. Significant differences between samples were analyzed with the paired Wilcoxon test and paired t test (n = 61, p < 0.01). b ADAR1 protein expression in tissue from three random patients. -, non-tumor oral mucosa; +, OSCC tissue. c Relationship between ADAR1 expression and TNM stage (p < 0.01). d Relationship between ADAR1 expression and primary tumor growth (p = 0.0958). e Relationship between ADAR1 expression and pathological grade (p = 0.0867). f Relationship between ADAR1 expression and lymph node metastasis (p = 0.05). g mRNA levels of ADAR1-p110 and ADAR1-p150 in HOK and OSCC cell lines. h ADAR1 protein expression in HOK and OSCC cell lines. The data were summarized from at least three independent experiments. *p < 0.05; **p < 0.01; ***p < 0.00; #p < 0.05; ##p < 0.01