ADAR1 promotes the epithelial-to-mesenchymal transition and stem-like cell phenotype of oral cancer by facilitating oncogenic microRNA maturation

Table 1 The association between ADAR1 and clinicopathological features of OSCC (n = 108)

Clinicopathological features	Total (n)	ADAR1		χ²	P
Clinicopathological features	Total (n)	Low (n)	High (n)	χ²	P
Gender
Male	64	34	30	0.6136	0.4334
Female	44	20	24	0.6136	0.4334
Age
< 60	45	20	25	0.9524	0.3291
≥ 60	63	34	29	0.9524	0.3291
T category
T1 + T2	66	43	23	15.58	< 0.0001
T3 + T4	42	11	31	15.58	< 0.0001
N category
N0	64	45	19	25.93	< 0.0001
N+	44	9	35	25.93	< 0.0001
Histology grade
Grade 1	80	37	43	0.7249	0.3945
Grade 2 + 3	28	17	11	0.7249	0.3945
TNM stage
I + II	50	32	18	7.299	0.0069
III + IV	58	22	36	7.299	0.0069

ADAR1 Adenosine deaminases acting on RNA, OSCC Oral squamous cell carcinoma, T Tumor size, N Lymph node, TNM Tumor-node-metastases, P P values of two-sided χ2 test; Both values signify P-value < 0.05

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