Fig. 7
From: DHRS2 mediates cell growth inhibition induced by Trichothecin in nasopharyngeal carcinoma
TCN up-regulates DHRS2 to inhibit NPC growth in vivo. a Effect of TCN on HK1 NPC cell xenograft in athymic BALB/c nude mice. Nude mice bearing HK1 cells were randomly separated into 3 groups (n = 6) and treated with corn oil (vehicle), TCN (1 mg/kg) or DDP (5 mg/kg) every other day for 5 weeks. Tumor volume was examined every other day and shown in the graph. b At the end of the experiment, the mice were sacrificed and the tumors were separated. Tumor mass of each group was weighed and shown in the graph. c During the experiment, body weight of the mice in each group was monitored and shown in the graph. d-e Images of tumor sections in each group stained with indicated antibodies. Antibody staining is in brown and nuclear counter staining is in blue. Scatter diagram shows Histoscore for the indicated antibody staining in tumor samples