Fig. 5

Expression of NF-κB target genes, p68 and RelA is positively correlated in human colon cancer tissues. a Representative images depicting IHC staining of Bcl-2, Bcl-xL, Survivin and XIAP conducted in tissue sections derived from human normal colon and colon carcinoma samples. Images were captured at 200X magnification. b Notched box plots showing the distribution of H-scores of Bcl-2, Bcl-xL, Survivin and XIAP in normal (n = 22) and colon carcinoma (n = 45) samples; Mann–Whitney U-values were calculated from H-scores. c Scatter plots representing the mean H-scores of p68, RelA and NF-κB target genes (Bcl-2, Bcl-xL, Survivin and XIAP) in normal and colon carcinoma tissue samples, respectively. d Spearman’s rank correlation coefficient (rs) between the mean H-scores of p68 and (e) RelA with each of the NF-κB target genes as indicated in the sub-figures was determined from both normal and colon carcinoma tissues in combination