Fig. 2
a Diagram showing steps in anti-HER2 gold nanoshell (GN) synthesis with corresponding TEM images. b UV-Vis absorption spectra of anti-HER2 GNs. c HER2 gene copy number, mRNA expression and immunostaining (brown) for BT474-R cell line (* P < 0.05). d Immunostaining of BT474-R cells incubated with trastuzumab-FITC (green, left panel). Dark field images of BT474-R cells incubated with anti-HER2 gold nanoshells (right panel)