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Table 1 Relationship between HMGB1 expression and clinicopathologic features in a validated cohort

From: HMGB1-mediated autophagy regulates sodium/iodide symporter protein degradation in thyroid cancer cells

Clinicopathologic

features

Low expression,

n = 18 (%)

High expression,

n = 18 (%)

P-value

Age (years)

  < 45

9 (50%)

10 (55.6%)

P = 0.738

  ≥ 45

9 (50%)

8 (44.4%)

 

Gender

 Male

7 (66.7%)

8 (22.2%)

P = 0.597

 Female

11 (33.3%)

10 (77.8%)

 

Tumor size (cm)

  < 1

12 (66.7%)

6 (33.3%)

P = 0.046

  ≥ 1

6 (33.3%)

12 (66.7%)

 

Lymph node metastasis

 No

13 (72.2%)

6 (33.3%)

P = 0.019

 Yes

5 (27.8%)

12 (66.7%)

 

Histological type

 PTC

9 (50%)

10 (55.6%)

P = 0.738

 FTC

9 (50%)

8 (44.4%)

 

Clinical stage

 I + II

13 (72.2%)

7 (38.9%)

P = 0.044

 III + IV

5 (27.8%)

11 (61.1%)