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Table 1 Relationship between HMGB1 expression and clinicopathologic features in a validated cohort

From: HMGB1-mediated autophagy regulates sodium/iodide symporter protein degradation in thyroid cancer cells

Clinicopathologic
features
Low expression,
n = 18 (%)
High expression,
n = 18 (%)
P-value
Age (years)
  < 45 9 (50%) 10 (55.6%) P = 0.738
  ≥ 45 9 (50%) 8 (44.4%)  
Gender
 Male 7 (66.7%) 8 (22.2%) P = 0.597
 Female 11 (33.3%) 10 (77.8%)  
Tumor size (cm)
  < 1 12 (66.7%) 6 (33.3%) P = 0.046
  ≥ 1 6 (33.3%) 12 (66.7%)  
Lymph node metastasis
 No 13 (72.2%) 6 (33.3%) P = 0.019
 Yes 5 (27.8%) 12 (66.7%)  
Histological type
 PTC 9 (50%) 10 (55.6%) P = 0.738
 FTC 9 (50%) 8 (44.4%)  
Clinical stage
 I + II 13 (72.2%) 7 (38.9%) P = 0.044
 III + IV 5 (27.8%) 11 (61.1%)