Journal of Experimental & Clinical Cancer Research

Table 2 Univariate and multivariate analysis of different prognostic parameters in 168 HCC patients

From: KIFC1 is activated by TCF-4 and promotes hepatocellular carcinoma pathogenesis by regulating HMGA1 transcriptional activity

Variable	Univariate analysis			Multivariate analysis
Variable	All cases	Mean survival (months)	P Values	HR (95% CI)	P Values
Age (years)			0.339
≤51	90	49.799
>51	78	69.089
Sex			0.061
Male	143	69.106
Female	25	43.696
AFP (ng/ml)			0.055
≤20	72	72.295
>20	96	53.431
HBsAg			0.329
negative	11	59.111
positive	157	66.402
Cirrhosis			0.829
No	99	57.617
Yes	69	66.272
Necrosis			0.179
No	76	60.350
Yes	92	63.514
Clinical stage			0.000		0.000
-	111	65.813		1
-	57	43.778		5.173 (2.456–10.894)
Histologic grade (WHO)			0.000		0.035
G1-G2	82	65.254		1
G3-G4^a	86	55.882		2.334 (1.063–5.126)
Tumor size (cm)			0.017		0.915
≤5	73	74.428
>5	95	49.049
Tumor multiplicity			0.000		0.478
Unifocal	128	61.089
Multifocal	40	50.483
Intravascular emboli			0.013		0.483
No	100	61.257
Yes	68	59.172
Recurrence			0.007		0.061
No	125	70.974
es	43	44.667
KIFC1			0.002		0.012
Low		74.153		1
High		45.568		2.371 (1.207–4.660)

^a:including 3 cases sarcomatoid liver cancer
P values less than 0.05 are in boldface

Back to article page

ISSN: 1756-9966

Contact us

Submission enquiries: Access here and click Contact Us
General enquiries: info@biomedcentral.com