Fig. 4
TET1 reverses EMT progress via the Wnt/β-catenin signaling pathway. a and b RNA array analysis of 84 EMT-associated genes in BX-TET1-OE and BX-TET1-NC cells, shown as a heatmap (log2-fold changes). c Heatmap (fold changes) of Wnt/β-catenin, TGF-β, and NOTCH signaling pathway changes in BX-TET-OE and SW1990-KO cells comparing respective negative controls. d Western blot analysis of key changes in gene expression in the Wnt/β-catenin pathway in BX-TET1-OE and BX-TET1-NC cells. e Western blot analysis of total β-catenin distribution in BXPC-3 and SW1990 cells. f Immunofluorescence staining of intracellular migration of active β-catenin in BX-TET1-OE and BX-TET1-NC cells