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Fig 6 | Journal of Experimental & Clinical Cancer Research

Fig 6

From: TET1-mediated DNA hydroxymethylation activates inhibitors of the Wnt/β-catenin signaling pathway to suppress EMT in pancreatic tumor cells

Fig 6

TET1 suppresses pancreatic tumor metastasis in vivo. a Metastasis in the orthotopic pancreatic metastatic model in nude mice was measured by bioluminescent signal on a bioluminescence IVIS. *P < 0.05. b Liver photos and H&E staining revealed distant metastasis in liver (blue arrows) (Original magnification, 20×. Enlarged graph, 80×). c IHC analysis of orthotopic implanted pancreatic tumors in nude mice (mag. 200×, left). Data summary (**P < 0.01, right)

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