Fig. 3

AHR nuclear translocation induced by 3MC is prevented by the AHR inhibitor CH223191 and the GPER antagonist G15. The AHR nuclear translocation in SkBr3 cells exposed for 1 h to 1 μM 3MC is prevented by 1 μM AHR inhibitor CH223191 and 100 nM GPER antagonist G15. Merge panels depict the overlap of the two fluorophores used to assess the nuclear translocation of AHR. Red signal: AHR. Blue signal: Nuclei. Images shown are representative of ten random fields from three independent experiments. Scale bar 12.06 μm