Fig. 4

YBX1/G3BP1 affects the migration and invasion abilities of RCC cells via SPP1. (a) Transwell assay was performed to determine the cell migration in treated ACHN cells. (b) Cell invasive assay was used to examine the cell invasion in treated ACHN cells. Upper panel: representative microscopic images. Lower panel: quantitative analysis. Data were presented as mean ± SD from three independent experiments, and five random microscopic fields were acquired in each experiment for quantification. Statistically significant differences were indicated: *, P < 0.05; **, P < 0.01; ***, P < 0.001