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Fig. 7 | Journal of Experimental & Clinical Cancer Research

Fig. 7

From: Peglated-H1/pHGFK1 nanoparticles enhance anti-tumor effects of sorafenib by inhibition of drug-induced autophagy and stemness in renal cell carcinoma

Fig. 7

HGFK1 inhibits sorafenib-induced autophagy via inhibiting NF-κB signaling pahtway. a Ketr-3 and ACHN cells were treated with sorafenib and/or rHGFK1, Bay 11–7082, then analyzed by Western-Blotting. b Ketr-3 cells were treated with sorafenib and/or rHGFK1, then analyzed by mRFP-GFP-LC3 puncta formation assay. c Ketr-3 cells were treated with sorafenib and/or Bay 11–7082, then analyzed the cell apoptosis by flow cytometer. Significant differences are denoted by *** for p < 0.001

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