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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: LncRNA FLVCR1-AS1 mediates miR-513/YAP1 signaling to promote cell progression, migration, invasion and EMT process in ovarian cancer

Fig. 2

FLVCR1-AS1 promoted cell proliferation and inhibited cell apoptosis abilities in OSC cells. a, b The transfection efficiency of OSC cells in response to transfection with FLVCR1-AS1 si-RNA or overexpression plasmid. FLVCR1-AS1 expression was inhibited when FLVCR1-AS1 was knockdown, while was promoted when FLVCR1-AS1 was overexpressed in both cell lines. c, d Cell proliferation was assayed in SKOV3 and OVCAR3 cells transfected with FLVCR1-AS1 si-RNA or overexpression plasmid using CCK8 at 0 h, 24 h, 48 h, 72 h and 96 h time point. e Colony formation assays were performed after transfection with FLVCR1-AS1 si-RNA or overexpression plasmid in both cell lines. f Apoptosis marker cleaved-caspase 3, Bax, and Bcl-2 were detected using western blot assay in SKOV3 and OVCAR3 cells transfected with FLVCR1-AS1 si-RNA and overexpression plasmid. *P < 0.05, **P < 0.01

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