Fig. 4

Linc00976 promotes the proliferation, invasion and metastasis of PC cells in vivo. a Typical image of nude mouse tumors (n = 6), b subcutaneous tumor weight, and c subcutaneous tumor volume, and d qRT-PCR assays showing the expression of Linc00976 in transplanted tumors. e Typical IHC staining images showing Ki-67 and PCNA expression in transplanted tumors under different experimental conditions. f the metastasis foci of per liver in liver metastasis model (n = 6). g Typical IHC staining of HE images showing metastasis loci in liver in indicated groups. h Kaplan-Meier survival curves for each experimental group (NC, Linc0097U and Linc00976D), for each group, n = 6. i Body weight changes for PANC-1 Linc00976U, Linc00976D and NC mice provided as mean ± SD, where each data point represents a different mouse