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Table 1 Correlation of galectin-1 with the histopathological parameters of HCC patients

From: Galectin-1 promotes hepatocellular carcinoma and the combined therapeutic effect of OTX008 galectin-1 inhibitor and sorafenib in tumor cells

Histopathological parameters T/NT < 2 (without Gal-1 overexpression) T/NT ≥ 2 (with Gal-1 overexpression) P-value
Sex
 Male 47 23 0.794
 Female 13 8
Cirrhotic liver
 Cirrhosis 18 6 0.402
 NT & hepatitis 22 14
HBsAg
 Positive 38 16 0.712
 Negative 6 4
Cellular differentiation
 Poor 22 8 0.130
 Differentiated 18 12
Tumor size
  > 5 cm 26 15 0.560
  ≤ 5 cm 14 5
Tumor encapsulation
 Absent 21 16 0.008*
 Present 27 4
Venous invasion
 Present 27 19 0.270
 Absent 29 12
Microsatellite
 Present 17 15 0.032*
 Absent 25 6
Direct liver invasion
 Present 11 7 0.551
 Absent 23 10
Tumor nodule
N ≥ 2 10 7 0.547
N = 1 29 13
  1. T Tumorous, NT non-tumorous, N number of tumor nodule, HBsAg Hepatitis B surface antigen, P < 0.05 is regarded as statistically significant
  2. *P < 0.05 is regarded as statistically significant