Fig. 2
From: Targeting T cell metabolism in the tumor microenvironment: an anti-cancer therapeutic strategy
Therapeutic targets and drugs against tumor metabolism. Tumor cells compete with immune cells in the microenvironment for the components required for their own metabolism, further inhibiting immune cell functions. Some drugs which focus on the metabolic processes of T cells and tumor cells contribute to the anti-tumor effect, such as PD-1/PD-L1 antibodies, metformin, and imatinib