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Table 1 Relationship between PLK3 expression and clinicopathologic variables in 116 CRC patients

From: Polo-like kinase 3 inhibits glucose metabolism in colorectal cancer by targeting HSP90/STAT3/HK2 signaling

Variable Case (n = 116) PLK3 expression P value
Negative Positive
Tissues     0.003
 Normal tisssues 116 49 67  
 Carcinoma 116 72 44  
Gender     0.936
 Male 68 42 26  
 Female 48 30 18  
Age     0.623
 ≤ 65 52 31 21  
 >65 64 41 23  
Location     0.301
 Left hemicolon 12 10 2  
 Right hemicolon 33 22 11  
 Sigmoid colon 24 14 10  
 Rectum 47 26 21  
Tumor size (cm)     0.008
 ≤ 4 × 3 53 26 27  
 > 4 × 3 63 46 17  
Tumor histology     
 Tubular 98 60 38 0.796
 Mucinous 16 11 5  
 Papillary 2 1 1  
Extent of invasion     0.332
 T1+ T2 31 17 14  
 T3+ T4 85 55 30  
Lymphatic metastasis     0.027
 N0 56 29 27  
 N1 + N2 60 43 17  
Metastasis     0.444
 M0 105 64 41  
 M1 11 8 3  
TNM stage     0.019
 I + II 55 28 27  
 III + IV 61 44 17  
CEA level     
 < 5.0 89 54 35 0.574
 ≥ 5.0 27 18 9