Polo-like kinase 3 inhibits glucose metabolism in colorectal cancer by targeting HSP90/STAT3/HK2 signaling

Table 1 Relationship between PLK3 expression and clinicopathologic variables in 116 CRC patients

Variable	Case (n = 116)	PLK3 expression		P value
Variable	Case (n = 116)	Negative	Positive	P value
Tissues				0.003
Normal tisssues	116	49	67
Carcinoma	116	72	44
Gender				0.936
Male	68	42	26
Female	48	30	18
Age				0.623
≤ 65	52	31	21
>65	64	41	23
Location				0.301
Left hemicolon	12	10	2
Right hemicolon	33	22	11
Sigmoid colon	24	14	10
Rectum	47	26	21
Tumor size (cm)				0.008
≤ 4 × 3	53	26	27
> 4 × 3	63	46	17
Tumor histology
Tubular	98	60	38	0.796
Mucinous	16	11	5
Papillary	2	1	1
Extent of invasion				0.332
T1+ T2	31	17	14
T3+ T4	85	55	30
Lymphatic metastasis				0.027
N0	56	29	27
N1 + N2	60	43	17
Metastasis				0.444
M0	105	64	41
M1	11	8	3
TNM stage				0.019
I + II	55	28	27
III + IV	61	44	17
CEA level
< 5.0	89	54	35	0.574
≥ 5.0	27	18	9

ISSN: 1756-9966