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Table 3 RNA sequencing data showing significant changes in expression mouse (MBMEC) and human (HBMEC) endothelial cells

From: Impact of Docetaxel on blood-brain barrier function and formation of breast cancer brain metastases

  mouse human
log2fc p-value log2fc p-value
Tubb2b 1.315 < 0.001 1.725 < 0.001
Tubb2a 1.212 < 0.001 1.523 < 0.001
Tuba4a 1.472 < 0.001 1.231 < 0.001
Tuba1a 1.231 < 0.001 1.364 < 0.001
Tspan2 −0.475 0.028 −1.513 0.007
  1. Differential expression analysis of mRNA levels of mouse (DTX, n = 3; ctrl, n = 2; DTX, 500 ng/mL) and human (DTX, n = 2; ctrl, n = 2; DTX, 50 ng/mL) primary cultured ECs after 24 h of DTX-treatment. Analysis was done using DESeq2 package, based on PCA plot. Outliers were excluded resulting in the above stated n