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Table 1 Univariate and multivariate analyses of clinicopathological characteristics, and CENPM with overall survival in TCGA LIHC cohort

From: Upregulation of CENPM promotes hepatocarcinogenesis through mutiple mechanisms

 Univariate analysisMultivariate analysis
CharacteristicsHR (95% CI)p-valueHR (95% CI)p-value
Gender
 (male vs female)0.862 (0.595–1.249)0.434  
Age, years
 (≥median vs. < median)1.012 (0.998–1.027)0.102  
Risk factors
 (alcohol consumption vs non-alcohol consumption)1.114 (0.828–1.499)0.476  
Histologic grade
 (G1 + G2 vs G3 + G4)1.215 (0.879–1.414)0.0389*  
Clinical stage
 (stage I + II vs stage III + IV)1.381 (1.149–1.660)0.000*  
Pathologic T stage (present vs. absent)1.673 (1.393–2.010)0.000*1.645 (1.192–2.269)0.002*
Pathologic N stage (present vs. absent)0.140 (0.045–0.442)0.007*0.169 (0.038–0.740)0.018*
Pathologic M stage (present vs. absent)0.089 (0.0221–0.362)0.000*0.335 (0.10–1.126)0.070*
CENPM
 (≥median vs. < median)1.043 (1.014–1.073)0.003*1.025 (0.799–1.057)0.032*
  1. HR, Hazard ratio, CI, Confidence interval. Bold italics indicate statistically significant values (*p < 0.05)