Fig. 1

LncRNA PAXIP1-AS1 is highly expressed in glioma and is associated with poor prognosis of patients with glioma. a, LncRNA PAXIP1-AS1 expression in glioma-related gene-expression dataset GSE104291. b, The expression of lncRNA PAXIP1-AS1 in glioma within the CRN database, 1 = normal tissue, 2 = glioma tissue. c, The expression of lncRNA PAXIP1-AS1 within the glioma tissues (n = 44) and normal brain tissues (n = 5) was examined by RT-qPCR, * p < 0.05 vs. normal brain tissues. d, Kaplan-Meier survival analysis of the correlation of lncRNA PAXIP1-AS1 expression with the prognosis of glioma patients, and Log-rank analysis for survival difference. e, RT-qPCR detection of the expression of lncRNA PAXIP1-AS1 in four glioma cell lines TJ905, HS 683, H4, SHG-44, and normal HAs, * p < 0.05 vs. HAs. f, RNA-FISH assay for the subcellular localization of lncRNA PAXIP1-AS1 in TJ905 cells (400 ×). The values are measurement data and expressed as mean ± standard deviation. Differences between two groups were compared using paired t test, and those between multiple groups were compared using one-way ANOVA with Tukey’s post hoc test. The Kaplan-Meier method was used to calculate the patient survival rate, and log-rank test was done for univariate analysis. Cell experiments were repeated three times independently