Fig. 2

Upregulation of miR-205 suppresses cell proliferation, invasion, and migration, but enhances apoptosis in prostate cancer. a proliferation of LNCaP cells after overexpression or inhibition of miR-205 detected using EdU assay (200 ×); b colony-forming ability of LNCaP cells after overexpression or inhibition of miR-205 detected using clonogenic assay; c apoptosis of LNCaP cells after overexpression or inhibition of miR-205 detected using flow cytometry; Abscissa represents apoptotic cells identified by Annexin V-FITC and ordinate represents dead cells identified by PI; d invasion and migration of LNCaP cells after overexpression or inhibition of miR-205 detected using Transwell assay (200 ×); *, p < 0.05. Measurement data were expressed as mean ± standard deviation; comparisons between two groups were analyzed using unpaired t-test; the experiment was repeated three times independently