Fig. 2

Downregulating miR-624-5p inhibited OS cell invasion and migration in vitro. a. miR-624-5p lentiviruses were successfully transfected into MG63 and U2OS cell lines (n = 3). b. sh-miR-624-5p #1 and sh-miR-624-5p #2 decreased the level of metastasis-related proteins in MG63 and U2OS (n = 3). c–f. The knockdown of miR-624-5p remarkably suppressed the invasion and migration of MG63 and U2OS cells (n = 4). g–h. 3D spheroid BME cell invasion assays confirm that downregulating miR-624-5p inhibited OS cell invasion (n = 4)