Fig. 5

Higher ZEB2 expression is linked to CMS4 and poor prognosis in colorectal tumors. a Kaplan Meier curve showing the relapse-free survival of 802 CRC patients separated on the basis of ZEB2 expression (red, low expression and blue, high expression). ***P < 0.001 based on log-rank test. b ZEB2 levels in CMS4 tumors as compared with CMSs 1–3. ***P < 0.001 based on one-way ANOVA, n = 2822. Outliers are depicted as crosses. c MKI67 levels in CMS4 as compared with CMSs 1–3. ***P < 0.001 based on one-way ANOVA, n = 2822. Outliers are depicted as crosses. Both the analysis of variance and the single post-hoc pairwise comparison in b and c are highly significant