Fig. 2

circFOXM1 promotes cell proliferation and tumor growth. a-b CCK-8 assay was performed to determine the viability in H1299 and H2170 cells with overexpressing or silencing circFOXM1. c-d Colony formation assay was employed to examine the colony formation abilities of H1299 and H2170 cells with overexpressing or silencingcircFOXM1. e-f Flow cytometry analysis showed an alteration in the proportion of cell in G1 phase and G2/M phase in H1299 and H2170 cells with overexpressing or silencing circFOXM1. g-i The volume and weight of subcutaneous xenograft tumors of H2170 cells isolated from nude mice (n = 6 mice per group). j Immunohistochemical staining for cell proliferation markers Ki-67 in subcutaneous xenograft tumors. *P < 0.05; **P < 0.01