Fig. 1
From: PERK/NRF2 and autophagy form a resistance mechanism against G9a inhibition in leukemia stem cells
Effects of G9a inhibition in leukemia cells and LSC-like cells. a, Flow cytometry analysis, based on annexin V/PI exclusion, of the fraction of apoptotic cells after treatment of AML cells and LSC-like cells with BIX-01294 for 48 h. b, H3K9 and H3K27 methylation, analyzed by western blotting, in KG1 cells treated with various concentrations of BIX-01294 for 24 h. c, Protein expression, analyzed by western blotting with the indicated antibodies, in KG1 and U937 cells treated with various concentrations of BIX-01294 for 48 h