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Fig. 6 | Journal of Experimental & Clinical Cancer Research

Fig. 6

From: Different p53 genotypes regulating different phosphorylation sites and subcellular location of CDC25C associated with the formation of polyploid giant cancer cells

Fig. 6

a Expression of cell cycle-related proteins in primary ovarian cancer with lymph node metastasis (group I), corresponding lymph node metastases (group II), primary ovarian cancer tissue without lymph node metastasis (group III), and serious borderline cystadenoma (group IV) (IHC, 200×). (a–d) CDC25C, (e–h) CDK1, (i–l) CHK1, and (m–p) CHK2 expressions in different groups. b Expression of protein kinase and P53 in primary ovarian cancer with lymph node metastasis (group I), corresponding lymph node metastases (group II), primary ovarian cancer tissue without lymph node metastasis (group III), and serious borderline cystadenoma (group IV) (IHC, 200×). (a–d) PLK1, (e–h) Aurora A, (i–l) pCDC25C-Ser216, and (m–p) positive and (q–t) negative P53 expressions in different groups. c Expression of cell cycle-related proteins in primary breast cancer (group I) and lymph node metastatic breast cancer (group II) (IHC, 200×). (a–b) CDC25C, (c–d) CDK1, (e–f) CHK1, and (g–h) CHK2 expressions in different groups. d Expression of protein kinase and P53 in primary breast cancer (group I) and lymph node metastatic breast cancer (group II) (IHC, 200×). (a–b) PLK1, (c–d) Aurora A, (e–f) pCDC25C-ser216, and (g–h) positive and (i–j) negative P53 expressions in different groups

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