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Table 2 Univariate and multivariate analysis for factors related to overall survival using the COX proportional hazard model

From: RETRACTED ARTICLE: The circular RNA 001971/miR-29c-3p axis modulates colorectal cancer growth, metastasis, and angiogenesis through VEGFA

Variable

Univariate analysis

Multivariate analysis

p-value

HR

95%CI

p-value

HR

95%CI

Gender

 Female

0.632

0.840

0.411–1.716

   

 Male

      

Age

  < 50

0.926

1.034

0.511–2.092

   

  ≥ 50

      

Tumorlocation

 

0.661

     

 Left

0.642

1.247

0.491–3.170

   

 Rectum

0.753

0.861

0.339–2.188

   

 Right

      

TNM

 I

0.000

  

0.000

  

 II

0.000

0.011

0.002–0.082

0.000

0.008

0.001–0.097

 III

0.000

0.022

0.004–0.111

0.000

0.012

0.001–0.138

 IV

0.000

0.070

0.016–0.306

0.000

0.047

0.011–0.212

Differentiation

 Low

0.231

1.547

0.757–3.162

   

 Moderat and High

      

Tumor size

  < 5

0.606

0.831

0.410–1.681

   

  ≥ 5

      

Lymph node metastasis

 

0.001

  

0.480

  

 N0

0.005

0.255

0.098–0.663

0.227

3.552

0.454–27.791

 N1

0.718

1.174

0.492–2.801

0.667

1.217

0.497–2.978

 N2

      

circ-001971

 High

      

 Low

0.000

6.785

2.764–16.654

0.001

6.456

2.060–20.232