Fig. 1
Bioinformatics analysis. a Box diagram of HOTAIR expression extracted from EC-related gene expression dataset GSE100942 in GEO database (https://www.ncbi.nlm.nih.gov/gds) using R language. The left blue box refers to the HOTAIR expression in normal samples and the right red box refers to the HOTAIR expression in EC samples (p = 1.137e-09). b. Survival curve of EC patients in relation to the expression of HOTAIR in the Ualcan database (http://ualcan.path.uab.edu/index.html) (p = 0.024). c Box diagram of MTHFR expression extracted from the EC-related gene expression dataset GSE100942 using R language. The left blue box refers to the HOTAIR expression in normal samples and the right red box refers to the HOTAIR expression in EC samples (p = 9.456e-13). d Co-expression analysis of lncRNA HOTAIR and MTHFR analyzed by MEM (https://biit.cs.ut.ee/mem/index.cgi) (p = 6.51e-04)