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Fig. 2 | Journal of Experimental & Clinical Cancer Research

Fig. 2

From: RETRACTED ARTICLE: M2 macrophage-derived extracellular vesicles promote gastric cancer progression via a microRNA-130b-3p/MLL3/GRHL2 signaling cascade

Fig. 2

Downregulation of miR-130b-3p inhibits GC cell survival, metastasis, and tube formation of HUEVCs in vitro.a The expression of miR-130b-3p in cells was detected by RT-qPCR. b CCK-8 assay was adopted to detect the viability of cells. c TUNEL assay was used to detect apoptosis of cells (200 ×). d Transwell assay was utilized to detect the migration of cells (200 ×). e Transwell assay was conducted to detect the invasion of cells (200 ×). f Matrigel-based angiogenic assays was performed to detect numbers of vessel-like tubes formed in vitro (100 ×) g, h: Western blot assay was used to detect the expression of proteins, normalized to GAPDH in each group. * p < 0.05 vs. agomir-NC-transfected cells; # p < 0.05 vs. antagomir-NC-transfected cells. One-way ANOVA was used among multiple groups, and two-way ANOVA was performed at different time points

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