Fig. 1
From: PDCD6 cooperates with C-Raf to facilitate colorectal cancer progression via Raf/MEK/ERK activation
PDCD6 is overexpressed in colorectal tumors and its overexpression is associated with poor prognosis in patients with colorectal tumors. a. GEPIA database analysis of PDCD6 expression in 623 patients with CORD and 410 patients with READ. b. Relative mRNA levels of PDCD6 in CRC patients was analyzed by qRT-PCR. The data are presented as means ±SDs; N = 22, and ***, P < 0.001. c. Representative immunohistochemical staining of PDCD6 on tissue microarrays containing CRC tissues and adjacent normal tissues. d. Tissue microarray data analysis of PDCD6 expression in 93 patients with CRC. The data are presented as the means ±SDs; N = 93; and ***, P < 0.001. e. Immunofluorescence staining of PDCD6 in patients with CRC tissues and adjacent normal tissues. f. Kaplan-Meier survival analysis of the correlation between PDCD6 expression and disease-free survival (DFS) in 423 patients with CRC. N = 423; DFS: P = 0.0103