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Table 2 Cox univariate regression analysis of the risk factors for death in CRC patients

From: Long noncoding RNA MAPKAPK5-AS1 promotes colorectal cancer progression by cis-regulating the nearby gene MK5 and acting as a let-7f-1-3p sponge

Variablesa

Overall survival

Relapse-free survival

 

HR (95% CI)

P

HR (95% CI)

P

MK5-AS1

0.476 (0.309–0.734)

0.01

0.538 (0.358–0.808)

0.003

Age (year)

0.777 (0.501–1.203)

0.258

0.667 (0.439–1.015)

0.059

Gender

0.854 (0.561–1.301)

0.463

0.885 (0.581–1.348)

0.57

Tumor invasion depth

0.463 (0.312–0.688)

< 0.001

0.48 (0.323–0.713)

< 0.001

Lymph node metastasis

0.319 (0.19–0.536)

< 0.001

0.355 (0.211–0.598)

< 0.001

Distant metastasis

0.112 (0.033–0.383)

< 0.001

0.228 (0.075–0.694)

0.009

TNM stage

0.412 (0.27–0.63)

< 0.001

0.426 (0.279–0.653)

< 0.001

  1. aMK5-AS1: low vs high; age: ≤60 vs > 60; gender: male vs female; Tumor invasion depth: T1–T2 vs T3–T4; Lymph node metastasis: N0 vs N1, N2, N3; TNM stage was ranked as I–II vs III–IV
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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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