Fig. 1

CD147 correlates with collective invasion in HCC. a. Representative images of HE staining (left) and immunofluorescent staining of E-cadherin, F-actin and nucleus of the invasive front of HCC tissues. Scale bar, 50 μm. b. Representative images of immunohistochemical staining of CD147 in invasive HCC tissues. Scale bar, 500 μm (middle), 200 μm (sides). c. Kaplan-Meier survival curves of HCC patients stratified into low- and high-expression of CD147 according to immunohistochemical staining. P value is determined by Log-rank (Mantel-Cox) test. d. CD147 expression in normal liver and liver cancer tissues. This data is derived from The Human Protein Atlas. *** p < 0.0001, Student’s t-test. e. Kaplan-Meier survival curves of HCC patients stratified into low- and high-expression of CD147. This data is derived from The Human Protein Atlas. P value is determined by Log-rank (Mantel-Cox) test