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Fig. 3 | Journal of Experimental & Clinical Cancer Research

Fig. 3

From: Long noncoding RNA ZFPM2-AS1 acts as a miRNA sponge and promotes cell invasion through regulation of miR-139/GDF10 in hepatocellular carcinoma

Fig. 3

Knockdown of lncRNA ZFPM2-AS1 inhibited cell proliferation, migration and invasion and promoted cell apoptosis in vitro. a The regulatory effect of short-hairpin ZFPM2-AS1 (sh-ZFPM2-AS1) transfection on the level of ZFPM2-AS1 in HCC cell lines (Data are expressed as the mean ± standard deviation, *** p < 0.001). b Effect of lncRNA ZFPM2-AS1 silencing on viability of HCC cell lines (Data are expressed as the mean ± standard deviation, *** p < 0.001). c and d Knockdown of lncRNA ZFPM2-AS1 significantly inhibited migration (c) and invasion (d) of HCC cells (Data are expressed as the mean ± standard deviation, *** p < 0.001). e Knockdown of lncRNA ZFPM2-AS1 significantly induced apoptosis of HCC cells (Data are expressed as the mean ± standard deviation, ** p < 0.01)

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