Fig. 5

Consistent expression changes of metastasis-related genes are induced by hypoxia and IL-1β in MDA-MB-231 cells, as evaluated by TaqMan™ Human Tumor Metastasis Array. a MDA-MB-231 cells were cultured upon normoxia or hypoxia (2% O2) in the presence or absence of the IL1R1 antagonist IL1R1a. b MDA-MB-231 cells were treated with vehicle or IL-1β alone or in combination with IL1R1a. Values were normalized to the Glucuronidase Beta (GUSB) expression, the colors indicate the log2 fold changes of gene expression upon the indicated conditions