Lysine-222 succinylation reduces lysosomal degradation of lactate dehydrogenase a and is increased in gastric cancer

Table 1 Associations between K222suc-LDHA expression and clinical pathological characteristics in patients with GC

Variable	n	Low (K222suc)	High (K222suc)	P value
Age				0.8090
≤ 60	26	12	14
> 60	47	20	27
Gender				0.0318
Male	46	25	21
Female	29	8	21
Pathological grade				0.0395
I-II	21	13	8
III-IV	55	19	36
Depth of invasion (T)				0.0125
T1-T2	17	12	5
T3-T4	60	21	39
Lymph node metastasis				0.0358
N0-N1	32	18	14
N2-N3	45	14	31
Distant metastasis (M)
Negative (M0)	67	27	40
Positive (M1)	9	5	4
Clinical stage				0.0318
I-II	30	18	12
III-IV	42	14	28

ISSN: 1756-9966