Fig. 7
From: TM4SF1 promotes EMT and cancer stemness via the Wnt/β-catenin/SOX2 pathway in colorectal cancer
TM4SF1 promotes tumourigenesis and tumour metastasis in mice. a, b Xenograft weight (mg) and size (cm) were measured. c Immunohistochemistry staining of TM4SF1, SOX2, β-catenin, CD133 and vimentin in xenograft tissues. d WB analysis of the expression of TM4SF1, SOX2, and β-catenin expression from sh-TM4SF1/scramble xenograft tumours. e Abolished tumour formation was found in the lungs of SW480 cell-injected mice. The statistical data of the tumour foci number and diameter are presented, and the black arrow marked metastatic nodules. H&E stained histological images of the lungs of the two groups of mice. *P < 0.05