Fig. 2
From: TMPRSS2, a SARS-CoV-2 internalization protease is downregulated in head and neck cancer patients
TMPRSS2 gene expression, HNSCC patient clinical variables and correlation with survival. a-c Box-plot analysis representing TMPRSS2 gene expression levels in tumoral HNSCC TCGA samples according to TP53 status (a), or HPV status (b), or N status (c). d-e Kaplan–Meier survival curves for TCGA HNSCC patients showing overall survival (OS) (d) and disease-free survival (DFS) (e), according to TMPRSS2 gene expression. f qRT-PCR analysis of TMPRSS2 expression levels in Cal-27 and Detroit-562 cell lines upon depletion of mutantp53 (sip53) or YAP (siYAP) or MYC (siMYC) compared to cells transduced with scramble molecules (value = 1). *p-value < 0.05