Table 4 Multivariate analysis of clinicopathological factors for disease-specific survival

Gender

Male/female

0.771

0.734 (0.415–1.859)

–

–

Age at diagnosis (years)

< 60/≥60

0.474

0.626 (0.537–2.552)

–

–

Differentiation

Well + moderately/poorly

0.331

1.422 (0.614–2.683)

–

–

Tumor size (cm)

< 5/≥5

0.002**

2.742 (0.326–4.663)

0.017*

3.471 (0.527–6.028)

Depth of invasion

T1 + T2/T3 + T4

0.095

1.116 (0.549–4.241)

–

–

Location

Colon/rectum

0.852

0.632 (0.412–1.743)

–

–

Lymph node status

N0/N1 + N2

0.153

2.571 (1.306–4.663)

0.216

2.154 (1.146–6.915)

TNM stage

I + II/III + IV

0.003**

13.145 (5.044–34.378)

0.004**

7.603 (2.521–33.109)

RP11-757G.15

High/low

0.008**

3.441 (1.471–8.005)

0.019*

2.015 (1.018–5.856)