Table 2 Correlation between HDAC3 expression and clinicopathological characteristics of CRC patients
From: HDAC3 deteriorates colorectal cancer progression via microRNA-296-3p/TGIF1/TGFβ axis
Clinicopathological characteristics | Cases | HDAC3 | P | |
|---|---|---|---|---|
(n = 121) | Low expression group (n = 52) | High expression group (n = 69) | ||
Age (years) | 0.854 | |||
≤ 60 | 54 | 24 | 30 | |
> 60 | 67 | 28 | 39 | |
Gender | 0.463 | |||
Male | 62 | 29 | 33 | |
Female | 59 | 23 | 36 | |
Location | 0.530 | |||
Left | 49 | 21 | 28 | |
Transverse | 7 | 3 | 4 | |
Right | 37 | 13 | 24 | |
Rectum | 28 | 15 | 13 | |
T stage | < 0.001 | |||
T1-T2 | 42 | 30 | 12 | |
T3-T4 | 79 | 22 | 57 | |
N stage | 0.004 | |||
N0 | 58 | 33 | 25 | |
N1-N3 | 63 | 19 | 44 | |
TNM | 0.024 | |||
I-II | 46 | 26 | 20 | |
III-IV | 75 | 26 | 49 | |
Histological grade | 0.003 | |||
Well | 14 | 12 | 2 | |
Moderate | 91 | 34 | 57 | |
Poor | 16 | 6 | 10 | |