Fig. 4

JM1-24-3 inhibits the proliferation, migration and invasion of melanoma cells a Treatment with JM1-24-3 (150 μg/mL) for seven days showed significant reduction in proliferation in A375 (52%), A2058 (76%) and WM266-4 (46%) cells as compared to irrelevant mAb treatment (p < 0.01). Colorimetric assays on the b migration of the WM266-4 cells treated with JM1-24-3 (150 μg/ml) showed significant reduction in migration (58%) and in c invasion assays (52%)