Fig. 2From: Novel insights into extrachromosomal DNA: redefining the onco-drivers of tumor progressionStructures of ecDNA and chrDNA. a. The nucleosomal organization of chrDNA is compact, and during cell division, DNA is packaged into chromosomes with centromeres. b. The nucleosomal organization of ecDNA is less compact than that of chrDNA, and ecDNA is circular without centromeresBack to article page