Fig. 7
From: Long noncoding RNA: a dazzling dancer in tumor immune microenvironment
Schematic diagram of the mechanism of lncRNAs in T cells. a Exosomal SNHG16 and RP11-323N12.5 derived from tumor cell are internalized by T cells to affect their differentiation, and ultimately generates immunosuppressive effect. b Exosomes abundant in substantial lncRNAs are secreted by exhausted CD8+ T cells. These exosomes can be taken up by non-exhausted CD8+ T cells, and thus weakens their anticancer effect