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Table 1 Overview of the genes with an altered expression level as effect of exposure to 12 serial doses of doxorubicin (P12), respectively 24 serial doses (p24) versus control cells (P0), on Hs578T and MDA-MB-231, considering a cut-off value for FC ±2 and p-value ≤0.05

From: New insights in gene expression alteration as effect of doxorubicin drug resistance in triple negative breast cancer cells

Cell line

Analysis

RNA species

Upregulated

Downregulated

Hs578T

P12 versus P0

Coding Genes

966

1069

lncRNAs

534

907

P24 versus P0

Coding Gene

1181

904

lncRNAs

732

785

MDA-MB-231

P12 versus P0

Gene

510

561

lncRNAs

412

423

P24 versus P0

Gene

629

586

lncRNAs

344

596