Fig. 5

Evodiamine inhibits H1975 tumor xenografts tumor growth by downregulation of MUC1-C. a The body weight of evodiamine-treated mice does not change compared to untreated animals. b-d Verifying the effect of evodiamine in vivo, shows that compared with the controls, tumor growth exhibits a suppressive trend starting at day 15 in the evodiamine-treated mice. e and f Western blot analysis shows that MUC1-C downregulation after evodiamine treatment