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Fig. 1 | Journal of Experimental & Clinical Cancer Research

Fig. 1

From: Gallbladder cancer-associated fibroblasts promote vasculogenic mimicry formation and tumor growth in gallbladder cancer via upregulating the expression of NOX4, a poor prognosis factor, through IL-6-JAK-STAT3 signal pathway

Fig. 1

GCAFs promote VM formation of GBC-SD cells in vitro (Phase contrast microscopy on 3-D cultures, × 200; A: Matrigel, B: rat-tail collagen-matrix). The tube number of vasculogenic-like networks in GBC-SD + GCAFs groups was significantly more than that of GBC-SD and GBC-SD + NFs groups (all *P < 0.05); furthermore, PAS positive, cherry-red materials found in granules and patches in the cytoplasm of GBC-SD cells appeared around the signal cell or cell clusters

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Journal of Experimental & Clinical Cancer Research

ISSN: 1756-9966

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