Characteristics | No. | OS | Â | Â | RFS | Â |
---|---|---|---|---|---|---|
 |  | HR (95% CI) | P |  | HR (95% CI) | P |
Univariate analysis | ||||||
 SIRT6, positive (vs. negative) | 15/26 | 5.855 (1.290-26.563) | 0.022 |  | 4.523 (1.245–16.434) | 0.022 |
Multivariate analysis | ||||||
 Tumor size, > 8 cm (vs. ≤ 8 cm) |  |  |  |  | 3.560 (1.055–12.009) | 0.041 |
 Distant metastasis, presence (vs. absence) |  | 48.868 (2.759-865.448) | 0.008 |  | 10.649 (1.186–95.614) | 0.035 |
 SIRT6, positive (vs. negative) |  | 6.988 (1.439–33.930) | 0.016 |  | 6.930 (1.727–27.814) | 0.006 |