Fig. 3

MiR-192-5p KO cells consumed more glucose from the environment. a Glucose concentration in culture medium from WT and 192KO lines of HLE and HLF cells infected with lentivirus pmiR-Ctrl or pmiR-192. b Cell viability of WT and 192KO lines for HLE and HLF cells infected with lentivirus pmiR-Ctrl or pmiR-192 and exposed to different doses of 2-DG. c 2-NBDG uptake by flow cytometry analysis of HLF-WT and -192KO cells infected with lentivirus pmiR-Ctrl (RFP) or pmiR-192 (RFP). d 2-NBDG uptake for all cells in co-culture system. HLF cells were infected with lentivirus pmiR-Ctrl (RFP) or pmiR-192 (RFP) and co-cultured with LX2, HL7702 or THP1 cells. Two-way ANOVA analysis was performed for (a, b) and student t-test was performed for (c, d). *, p < 0.05